trans-Ferulic Acid CAS NO.537-98-4

Min.Order: 10 Milligram
Payment Terms: T/T
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trans-Ferulic Acid
537-98-4
standard supplier in China

Quick Details

ProName: trans-Ferulic Acid
CasNo: 537-98-4
Molecular Formula: C10H10O4
Appearance: detailed see specifications
Application: analysis,activity test,Botanical Refer...
DeliveryTime: 1-3?working?days?after?confirming?the?...
PackAge: According to the clients requirement.
Port: China main port
ProductionCapacity: 1 Metric Ton/Day
Purity: ≥98%
Storage: Store at 2~8°C
Transportation: by air or by ocean shipping
LimitNum: 10 Milligram
Plant of Origin: Chinese herbal medicine
Testing Method: NMR/MS/HPLC
Product Ecification: 1mg-1kg
Heavy Metal: <10ppm
Voluntary Standards: company standard
Storage: Store in dry, dark and ventilated plac...
PackAge: Brown vial HDPE plastic bottle

Superiority

Hubei CuiRan Biotechnology Co., Ltd is a leading company in the research, development, manufacture and marketing of High Quality Phytochemicals and Extracts(especially Active Ingredients from Traditional Chinese Medicine，Traditional Chinese Medicine), Natural Active Pharmaceutical Ingredients worldwide. From small quantities for R&D or reference standard, to large quantities for customizing or manufacturing, Biopurify emphasizes on consistent and reliable services for his customers.
With excellent quality products and good service, we have clients from more than dozens countries and regions, and we pride ourselves in providing our customers with a total satisfaction experiences.
We are doing our best to be your reliable partner for high quality Phytochemicals and Reference Standards from china.

Our main services:
A. Supply active ingredients and reference standards ofTraditional Chinese Medicine, from mgs to kgs scale.
B. Custom extraction and purification, target Herb Active Ingredients
C. Custom synthesis and semi-synthesis for Natural Active Ingredients
D. CR, CM and PD services from lab scale, pilot scale to commercial scale(GMP is also available)
E.Traditional Chinese Medicine compounds library

1.Provide traditional Chinese medicine reference materials and natural active ingredients;
2.More than 2200 compounds are available for selection, continuously building high-quality natural product libraries for drug research and development;
3.Provide various screening libraries and more inhibitor products;
4.Provide separation and structural determination of natural products;
5.Laboratory scale pilot to commercial scale collaborative research and process development services.More than 180 experiences in phytochemistry (still increasing)
Each product has passed very strict testing (NMR/MS/HPLC)
Agents from many countries

General tips：For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging：1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition：Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Details

Chemical Properties of trans-Ferulic acid

Cas No.	537-98-4
PubChem ID	445858	Appearance	Light yellow powder
Formula	C₁₀H₁₀O₄	M.Wt	194.18
Type of Compound	Phenylpropanes	Storage	Desiccate at -20°C
Synonyms	Coniferic acid; 4-Hydroxy 3-methoxy trans-cinnamic acid
Solubility	Soluble in diethyl ether, ethanol, ethyl acetate, methanol and hot water
Chemical Name	(E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
SMILES	COC1=C(C=CC(=C1)C=CC(=O)O)O
Standard InChIKey	KSEBMYQBYZTDHS-HWKANZROSA-N
Standard InChI	InChI=1S/C10H10O4/c1-14-9-6-7(2-4-8(9)11)3-5-10(12)13/h2-6,11H,1H3,(H,12,13)/b5-3+
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging	1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment.
Shipping Condition	Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of trans-Ferulic acid

1 Allium sp. 2 Anagallis sp. 3 Angelica sp. 4 Apium sp. 5 Avena sp. 6 Brassica sp. 7 Bupleurum sp. 8 Calendula sp. 9 Catalpa sp. 10 Chamaemelum sp. 11 Cichorium sp. 12 Cicuta sp. 13 Cimicifuga sp. 14 Cinnamomum sp. 15 Citrus sp. 16 Cocos sp. 17 Consolida sp. 18 Cornus sp. 19 Elaeis sp. 20 Euphorbia sp. 21 Euphrasia sp. 22 Ferula sp. 23 Foeniculum sp. 24 Geranium sp. 25 Haematoxylum sp. 26 Hedera sp. 27 Humulus sp. 28 Illicium sp. 29 Iris sp. 30 Jacaranda sp. 31 Linum sp. 32 Lycopodium sp. 33 Lycopus sp. 34 Manihot sp. 35 Maytenus sp. 36 Melissa sp. 37 Mentha sp. 38 Mentzelia sp. 39 Musa sp. 40 Olea sp. 41 Ononis sp. 42 Piper sp. 43 Potentilla sp. 44 Pterocarpus sp. 45 Rhododendron sp. 46 Ricinus sp. 47 Rosmarinus sp. 48 Salvia sp. 49 Sambucus sp. 50 Scrophularia sp. 51 Secale sp. 52 Sesamum sp. 53 Sinapis sp. 54 Syzygium sp. 55 Tanacetum sp. 56 Thymus sp. 57 Urtica sp. 58 Verbascum sp. 59 Veronica sp. 60 Virola sp. 61 Viscum sp. 62 Zingiber sp.

Preparing Stock Solutions of trans-Ferulic acid

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	5.1499 mL	25.7493 mL	51.4986 mL	102.9972 mL	128.7465 mL
5 mM	1.03 mL	5.1499 mL	10.2997 mL	20.5994 mL	25.7493 mL
10 mM	0.515 mL	2.5749 mL	5.1499 mL	10.2997 mL	12.8747 mL
50 mM	0.103 mL	0.515 mL	1.03 mL	2.0599 mL	2.5749 mL
100 mM	0.0515 mL	0.2575 mL	0.515 mL	1.03 mL	1.2875 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

References on trans-Ferulic acid

Pediococcus Pentosaceus from the Sweet Potato Fermented Ger-Minated Brown Rice Can Inhibit Type I Hypersensitivity in RBL-2H3 Cell and BALB/c Mice Models.[Pubmed:34576749]

Microorganisms. 2021 Aug 31;9(9). pii: microorganisms9091855.

In this study, the effect of GBR fermented with the Pediococcus pentosaceus SP024 strain on IgE/Ag mediated passive cutaneous anaphylaxis (PCA) was investigated. Protocatechuic acid and trans-Ferulic acid levels in GBR-SP024 increased more than those in unfermented GBR, respec-tively. The inhibitory activity of GBR-SP024 on beta-hexosaminidase release and the level of proin-flammatory cytokine mRNA expression (tumor necrosis factor-alpha (TNF-alpha) and interleukin 4 (IL-4)) was observed in IgE/Ag-stimulated RBL-2H3 cells. Western blot analysis showed that GBR-SP024 significantly inhibited the phosphorylation of the linker for activation of T cell (LAT) and nuclear factor-kappaB (NF-kappaB) in IgE/Ag-stimulated RBL-2H3 cells. Further, we investigated the anti-allergic effect of GBR-SP024 using PCA murine model. The number of infiltrated immune cells and degranulated mast cells in GBR-SP024 treated dermis was lower than that in the GBR-treated mice. In addition, mRNA expression of 5-lipoxygenase (5-LOX) in the dermis of ear tissue declined in the GBR-SP024-treated group, compared to that in the GBR group. GBR-SP024 was also more effective than GBR at reducing the levels of IL-33 protein expression in IgE/Ag-stimulated BALB/c mice. Our study suggests the potential usage of GBR-SP024 as a dietary supplement or an adjuvant for treating IgE-dependent-allergic diseases.

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