11-Oxomogroside III CAS NO.952481-53-7

Hubei CuiRan Biotechnology Co., Ltd is a leading company in the research, development, manufacture and marketing of High Quality Phytochemicals and Extracts(especially Active Ingredients from Traditional Chinese Medicine，Traditional Chinese Medicine), Natural Active Pharmaceutical Ingredients worldwide. From small quantities for R&D or reference standard, to large quantities for customizing or manufacturing, Biopurify emphasizes on consistent and reliable services for his customers. 
With excellent quality products and good service, we have clients from more than dozens countries and regions, and we pride ourselves in providing our customers with a total satisfaction experiences.
We are doing our best to be your reliable partner for high quality Phytochemicals and Reference Standards from china.
 
Our main services:
A. Supply active ingredients and reference standards ofTraditional Chinese Medicine, from mgs to kgs scale.
B. Custom extraction and purification, target Herb Active Ingredients
C. Custom synthesis and semi-synthesis for Natural Active Ingredients
D. CR, CM and PD services from lab scale, pilot scale to commercial scale(GMP is also available)
E.Traditional Chinese Medicine compounds library
 

1.Provide traditional Chinese medicine reference materials and natural active ingredients;
2.More than 2200 compounds are available for selection, continuously building high-quality natural product libraries for drug research and development;
3.Provide various screening libraries and more inhibitor products;
4.Provide separation and structural determination of natural products;
5.Laboratory scale pilot to commercial scale collaborative research and process development services.More than 180 experiences in phytochemistry (still increasing)
Each product has passed very strict testing (NMR/MS/HPLC)
Agents from many countries

General tips：For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging：1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition：Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Chemical Properties of 11-Oxomogroside III

Source of 11-Oxomogroside III

The fruits of Siraitia grosvenorii Swingle.

Biological Activity of 11-Oxomogroside III

Protocol of 11-Oxomogroside III

Preparing Stock Solutions of 11-Oxomogroside III

References on 11-Oxomogroside III

[Simultaneous determination of six cucurbitane triterpene glycosides in Siraitia grosvenorii fruits using high performance liqid chromatography].[Pubmed:18959251]

Se Pu. 2008 Jul;26(4):504-8.

Siraitia grosvenorii, a traditional Chinese fruit, belongs to the family Cucurbitaceae and has been used as a pulmonary demulcent and emollient for the treatment of dry cough, sore throat, dire thirst, and constipation in folk medicine. A high performance liquid chromatographic method was developed for simultaneous determining the contents of mogroside V, mogroside IV A, mogroside III, 11-Oxomogroside III, mogroside II E and 11-oxomogroside II E in Siraitia grosvenorii fruits. The chromatographic analysis was carried out on a ZORBAX SB-C18 column (150 mm x 4.6 mm, 5 microm). The mobile phase was water (A) and acetonitrile (B) with gradient elution (0-3 min, 20% B - 30% B; 3-8 min, 30% B - 35% B; 8-9 min, 35% B). The flow rate was maintained at 0. 8 mL/min. The detection wavelength was set at 203 nm and the column temperature was controlled at 30 degrees C. The sample injection volume was 10 microL. The calibration curves were linear over the ranges of 0.04 - 1.0 mg/mL, 0.011 - 0.68 mg/mL, 0.010 - 0.80 mg/mL, 0.0097 - 0.58 mg/mL, 0.025 - 1.0 mg/mL and 0.013 - 0.76 mg/mL (r > 0.999 1) for the above cucurbitane triterpene glycosides, respectively. The average recoveries were 99. 65% for mogroside V , 101.6% for mogroside IV A, 97. 05% for mogroside m, 103. 1% for 11-oxomogroside I, 99. 25% for mogroside II E, and 103.0% for 11-oxomogroside II E, with the relative standard deviations of 0.83%, 3.1%, 1.9%, 3.3%, 0.59% and 2.0%, respectively. This simple, rapid and accurate method is suitable for quality control and determination of raw materials and products of Siraitia grosvenorii fruits.

Cucurbitane glycosides from unripe fruits of Siraitia grosvenori.[Pubmed:17603208]

Chem Pharm Bull (Tokyo). 2007 Jul;55(7):1082-6.

Studies on the constituents of the unripe fruits of Siraitia grosvenori led to the isolation of three new cucurbitane triterpene glycosides, 11-Oxomogroside III (10), 11-dehydroxymogroside III (11), and 11-oxomogroside IV A (12). Their structures were determined on the basis of detailed analyses of 1D, 2D-NMR spectroscopic methods. All of the compounds isolated from the unripe fruits of S. grosvenori were tested for cytotoxic activities against tumor cells, HCT-116 and SMMC-7721.

Description

11-Oxomogroside III is a cucurbitane triterpene glycoside isolated from in Siraitia grosvenorii fruits.

Keywords:

11-Oxomogroside III,952481-53-7,Natural Products, buy 11-Oxomogroside III , 11-Oxomogroside III supplier , purchase 11-Oxomogroside III , 11-Oxomogroside III cost , 11-Oxomogroside III manufacturer , order 11-Oxomogroside III , high purity 11-Oxomogroside III