Isomangiferin CAS NO.24699-16-9

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General tips：For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
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Chemical Properties of Isomangiferin

Source of Isomangiferin

1 Asplenium sp. 2 Belamcanda sp. 3 Cyclopia sp. 4 Mangifera sp. 5 Swertia sp.

Biological Activity of Isomangiferin

Protocol of Isomangiferin

Preparing Stock Solutions of Isomangiferin

References on Isomangiferin

Antioxidant C-glucosylxanthones from the leaves of Arrabidaea patellifera.[Pubmed:18950229]

J Nat Prod. 2008 Nov;71(11):1887-90.

Chemical investigation of the methanol extract from the leaves of Arrabidaea patellifera, a Bignoniaceae from Panama, afforded mangiferin, Isomangiferin, and six new derivatives (3'-O-p-hydroxybenzoylmangiferin, 3'-O-trans-coumaroylmangiferin, 6'-O-trans-coumaroylmangiferin, 3'-O-trans-cinnamoylmangiferin, 3'-O-trans-caffeoylmangiferin, and 3'-O-benzoylmangiferin). All these compounds had antioxidant and radical-scavenging activities, and four of them were relatively active in vitro against Plasmodium falciparum. The structures were determined by spectrometric and chemical methods, including 1D and 2D NMR experiments and MS analysis.

[Antiviral effect of mangiferin and isomangiferin on herpes simplex virus].[Pubmed:2554669]

Zhongguo Yao Li Xue Bao. 1989 Jan;10(1):85-90.

Using tissue culture techniques the present study assured us of the merits of mangiferin and Isomangiferin in the antiviral action against HSV-1. Utilizing 4 main patterns for evaluating drug effectiveness (ie intratube drug-on-virus direct action, simultaneous addition of drug-virus-inoculum to cell bottle, virus inoculation preceding drug addition, and drug addition followed by virus inoculation), it was readily found by logarithm determination of HSV-I inhibition that Isomangiferin was superior to such control drugs as acyclovir, idoxuridine, and cyclocytidine in logarithm by 0.27-0.50, and that mangiferin was lower than Isomangiferin in logarithm by 0.53. The average plaque reduction rates of mangiferin and Isomangiferin were 69.5% and 56.8%, respectively. All in all, the antiviral effect of mangiferin and Isomangiferin was attributed presumably to their capability to inhibit virus replication within cells.

Description

Isomangiferin, a natural product, is reported to have antiviral activity.

Keywords:

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