Epicatechin；L-Epicatechin；DL-Catechin CAS NO.7295-85-4

Min.Order: 10 Milligram
Payment Terms: T/T
Available Specifications:

Product Details

Keywords

7295-85-4
Epicatechin；L-Epicatechin；DL-Catechin
High quality

Quick Details

ProName: Epicatechin；L-Epicatechin；DL-Catechin
CasNo: 7295-85-4
Molecular Formula: C15H14O6
Appearance: detailed see specifications
Application: analysis,activity test,Botanical Refer...
DeliveryTime: 1-3 working days after confirming
PackAge: According to the clients requirement.
Port: China main port
ProductionCapacity: 1 Metric Ton/Day
Purity: HPLC≥98%
Storage: Store at 2~8°C
Transportation: by air or by ocean shipping
LimitNum: 10 Milligram
Plant of Origin: Chinese herbal medicine
Testing Method: NMR/MS/HPLC
Product Ecification: 1mg-1kg
Heavy Metal: <10ppm
Voluntary Standards: Company standard

Superiority

Hubei CuiRan Biotechnology Co., Ltd is a leading company in the research, development, manufacture and marketing of High Quality Phytochemicals and Extracts(especially Active Ingredients from Traditional Chinese Medicine，Traditional Chinese Medicine), Natural Active Pharmaceutical Ingredients worldwide. From small quantities for R&D or reference standard, to large quantities for customizing or manufacturing, Biopurify emphasizes on consistent and reliable services for his customers.
With excellent quality products and good service, we have clients from more than dozens countries and regions, and we pride ourselves in providing our customers with a total satisfaction experiences.
We are doing our best to be your reliable partner for high quality Phytochemicals and Reference Standards from china.

Our main services:
A. Supply active ingredients and reference standards ofTraditional Chinese Medicine, from mgs to kgs scale.
B. Custom extraction and purification, target Herb Active Ingredients
C. Custom synthesis and semi-synthesis for Natural Active Ingredients
D. CR, CM and PD services from lab scale, pilot scale to commercial scale(GMP is also available)
E.Traditional Chinese Medicine compounds library

1.Provide traditional Chinese medicine reference materials and natural active ingredients;
2.More than 2200 compounds are available for selection, continuously building high-quality natural product libraries for drug research and development;
3.Provide various screening libraries and more inhibitor products;
4.Provide separation and structural determination of natural products;
5.Laboratory scale pilot to commercial scale collaborative research and process development services.More than 180 experiences in phytochemistry (still increasing)
Each product has passed very strict testing (NMR/MS/HPLC)
Agents from many countries

General tips：For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging：1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition：Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Details

Chemical Properties of DL-Catechin

Cas No.	7295-85-4	SDF
PubChem ID	1203	Appearance	White powder
Formula	C₁₅H₁₄O₆	M.Wt	290.3
Type of Compound	Flavonoids	Storage	Desiccate at -20°C
Synonyms	13392-26-2;L-Epicatechin
Solubility	Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name	2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-chromene-3,5,7-triol
SMILES	C1C(C(OC2=CC(=CC(=C21)O)O)C3=CC(=C(C=C3)O)O)O
Standard InChIKey	PFTAWBLQPZVEMU-UHFFFAOYSA-N
Standard InChI	InChI=1S/C15H14O6/c16-8-4-11(18)9-6-13(20)15(21-14(9)5-8)7-1-2-10(17)12(19)3-7/h1-5,13,15-20H,6H2
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging	1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment.
Shipping Condition	Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of DL-Catechin

The bark of Taxus yunnanensis

Biological Activity of DL-Catechin

Description

(+)-Catechin hydrate has antioxidant activity and is effective in reducing oxidative stress. (+)-Catechin hydrate acts as mixed type inhibitor with predominant inhibition at anodic site, it has inhibiting action on the corrosion of mild steel in hydrochloric acid.

Targets

ROS

In vivo

Effect of (+)-catechin hydrate on oxidative stress induced by high sucrose and high fat diet in male Wistar rats.[Pubmed: 24266106]

Indian J Exp Biol. 2013 Oct;51(10):823-7.

METHODS AND RESULTS:
Increased lipid peroxidation and reduced glutathione levels in liver of rats fed high sucrose high fat (HSHF) diet were normalized by concomitant administration of (+)-Catechin hydrate. Plasma non-enzymatic antioxidants viz. alpha-tocopherol, ascorbic acid and total thiols decrease were also significantly less in rats administered with (+)-Catechin hydrate concomitantly with HSHF diet. Thus the present results indicate that (+)-Catechin hydrate has antioxidant activity and is effective in reducing oxidative stress.
CONCLUSIONS:
The study is of clinical importance as oxidative stress is known to be the cause of many clinical manifestations viz. cancer, Parkinson's disease, atherosclerosis, heart failure, myocardial infarction and many other diseases.

Protocol of DL-Catechin

Kinase Assay

Electrochemical, Thermodynamic and Adsorption Studies of (+)-Catechin Hydrate as Natural Mild Steel Corrosion Inhibitor in 1 M HCl[Reference: WebLink]

Int. J. Electrochem.Sc., 2011, 6(2011):1396-414.

The inhibiting action of (+)-Catechin hydrate on the corrosion of mild steel in hydrochloric acid has been studied.
METHODS AND RESULTS:
The results from weight loss, Tafel polarization and electrochemical impedance measurements consistently identify (+)-Catechin hydrates as a good inhibitor. Polarization curves indicate that (+)-Catechin hydrate act as mixed type inhibitor with predominant inhibition at anodic site. Impedance spectroscopy revealed that the corrosion of mild steel in hydrochloric solution was influenced to some extent by charge transfer. The inhibition efficiencies (IE %) of (+)-Catechin hydrate was decreased exponentially with the temperatures. Surface analyses via scanning electron microscope (SEM) show a significant morphological improvement on the mild steel surface in addition of (+)-Catechin hydrate.
CONCLUSIONS:
The inhibitive action of (+)-Catechin hydrate follows the Langmuir adsorption model.

Preparing Stock Solutions of DL-Catechin

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	3.4447 mL	17.2236 mL	34.4471 mL	68.8942 mL	86.1178 mL
5 mM	0.6889 mL	3.4447 mL	6.8894 mL	13.7788 mL	17.2236 mL
10 mM	0.3445 mL	1.7224 mL	3.4447 mL	6.8894 mL	8.6118 mL
50 mM	0.0689 mL	0.3445 mL	0.6889 mL	1.3779 mL	1.7224 mL
100 mM	0.0344 mL	0.1722 mL	0.3445 mL	0.6889 mL	0.8612 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.